Comments on: Grapefruit and Low Dose Birth Control Pills - a Risky Cocktail http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/ PLAN your 'contraception career'- learn about LOW DOSE birth control, side effects and contraceptive options Fri, 18 May 2012 08:42:47 +0000 http://wordpress.org/?v=2.3 By: day http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2604 day Wed, 01 Jun 2011 13:22:45 +0000 http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2604 Where is the scientific study which supports your conclusions? Grapefruit causes a decrease in CYP3A levels in the intestine, according to the University of Arizona's Center for Education and Research on Therapeutics. Other citrus fruits eg. oranges, pineapples do not contain as much of the compound that decreases the CY3PA levels so don't present the same risk of reducing the effectiveness of your birth-control pill. However, some other citrus fruits eg. such as limes and Seville oranges may have an effect on other medications. Refs: . <em>Bailey DG, Spence JD, Munoz C, Arnold JMO. Interaction of citrus juices with felodipine and nifedipine. Lancet 1991; 337:268-9. Lown KS, Bailey DG, Fontana RJ, et al. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.</em> Where is the scientific study which supports your conclusions?

Grapefruit causes a decrease in CYP3A levels in the intestine, according to the University of Arizona’s Center for Education and Research on Therapeutics. Other citrus fruits eg. oranges, pineapples do not contain as much of the compound that decreases the CY3PA levels so don’t present the same risk of reducing the effectiveness of your birth-control pill. However, some other citrus fruits eg. such as limes and Seville oranges may have an effect on other medications.
Refs: . Bailey DG, Spence JD, Munoz C, Arnold JMO. Interaction of citrus juices with felodipine and nifedipine. Lancet 1991; 337:268-9.
Lown KS, Bailey DG, Fontana RJ, et al. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression.

]]> By: Ann Onnimus http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2551 Ann Onnimus Wed, 06 Apr 2011 01:11:08 +0000 http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2551 I don't get it. You just said the grapefruit interferes with the ESTROGEN absorption, and then you turn around and say that Depo-provera (which is progestin ONLY) can also be affected! Which one is it?? You didn't happen to mention these, but contraceptive implants are primarily progestin-only, as far as I'm aware. Would their effectiveness also be affected? Hello Ann, Thank you for your comment. I wish to point out that the NB at the bottom of the post refers to the para ABOVE, i.e OTHER <strong>medications</strong> can affect Depo and other types of low dose birth control. Grapefruit affects estogen absorption not progestin. Apologies if this was misleading or ambiguous and thank you for helping me to confirm this point. Yes, you are correct, contraceptive implants do not contain estrogen - they contain either levonorgestrel or etonogestrel (synthetic forms of progestin) so their effectiveness would not be reduced by grapefruit. Kind regards Carole I don’t get it. You just said the grapefruit interferes with the ESTROGEN absorption, and then you turn around and say that Depo-provera (which is progestin ONLY) can also be affected! Which one is it??

You didn’t happen to mention these, but contraceptive implants are primarily progestin-only, as far as I’m aware. Would their effectiveness also be affected?

Hello Ann, Thank you for your comment. I wish to point out that the NB at the bottom of the post refers to the para ABOVE, i.e OTHER medications can affect Depo and other types of low dose birth control. Grapefruit affects estogen absorption not progestin. Apologies if this was misleading or ambiguous and thank you for helping me to confirm this point. Yes, you are correct, contraceptive implants do not contain estrogen - they contain either levonorgestrel or etonogestrel (synthetic forms of progestin) so their effectiveness would not be reduced by grapefruit. Kind regards Carole

]]> By: admin http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2429 admin Tue, 31 Aug 2010 07:41:58 +0000 http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2429 Hi Lucas, My daughter has a great grapefruit tree too but I cannot make the most of it! Please check with your girlfriend if she takes oral BC pills that the one she is taking is progestin only - otherwise I'd be checking quickly with the doctor that the no. of grapefruit she eats is not reducing the effectiveness of her birth control. Cheers Carole Hi Lucas, My daughter has a great grapefruit tree too but I cannot make the most of it! Please check with your girlfriend if she takes oral BC pills that the one she is taking is progestin only - otherwise I’d be checking quickly with the doctor that the no. of grapefruit she eats is not reducing the effectiveness of her birth control. Cheers Carole

]]> By: Lucas Watson http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2410 Lucas Watson Fri, 11 Jun 2010 03:12:47 +0000 http://contraceptivereviewer.com/grapefruit-and-low-dose-birth-control-pills-a-risky-cocktail/#comment-2410 my girlfriend has a grape fruit plantation in their backyard and we always taste some of the harvest.-`* my girlfriend has a grape fruit plantation in their backyard and we always taste some of the harvest.-`*

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